The North London derby often means goals - and plenty of them - so swiftly confine your Arsenal and Tottenham defenders to the scrapheap and look further afield.
Manchester United and Chelsea look prime candidates for guaranteed points. United face swine-flu stricken Blackburn at Old Trafford but have a potential defensive crisis of their own, while Chelsea come off the back of their 4-0 thrashing of Bolton in midweek with a repeat of the clash at the Reebok Stadium.
Choose 'em: Edwin van der Sar (11.18) is not the cheapest but is surely nailed on for a clean sheet against Blackburn, while Shay Given (7.62) is good value with Manchester City visiting Portsmouth, who are still winless at Fratton Park. The best bet may well lie in the hands of the returning Thomas Sorensen (9.89), who against Wolves at the Britannia Stadium could earn you good points.
Lose 'em: Not even The Fantasist can justify picking Paul Robinson (3.45) this week as Blackburn take on the champions at Old Trafford. Jussi Jaaskelainen (7.27) is appalling value, while bargain-seekers who have enjoyed backing Vito Mannone (7.67) should not stick with their man as he could well be replaced by Manuel Almunia for the visit of Spurs.
Choose 'em: John O'Shea (6.42) has a price befitting such an underrated player and the defender will be a proverbial hub of points against Blackburn, especially with Rio Ferdinand and Nemanja Vidic doubts for Manchester United, Jonny Evans (8.73) comes back into the reckoning for the brave opportunists. Graham Alexander (5.63) represents terrific value and may even step up to grab you a cheeky penalty.
Lose 'em: Ledley King (11.09) should be banished from your team with Spurs travelling to the Emirates to face free-scoring Arsenal, while the exceptionally-overpriced Gary CahillLiam Ridgewell
Choose 'em: Joe Cole (7.91) is as prudent an investment as you could wish for with the Chelsea playmaker hungry for another big performance against Bolton. Yossi BenayounStiliyan Petrov (7.53) into your side could prove a wise move.
Lose 'em: If you eagerly look to see how much David Bentley (10.83) is looking to snap up Aaron Lennon's replacement on the cheap you will be sorely disappointed, and picking him up against Arsenal would be an atrocious piece of business. Matthew Taylor is hideously overpriced at 16.89 and should be avoided against Chelsea, while David Dunn's (12.16) can be thrown in the same direction with Chelsea coming to town. (7.60) has proved good value so far this season, but a hungry Manchester City could hit his stock hard. (10.60) is hardly cheap but with the inventive Israeli playing just off Fernando Torres against Fulham he could be lucrative. Aston Villa face both Everton and West Ham in gameweek 10, so slipping (11.40) stock has rocketed of late but he should be removed for the trip to Old Trafford.
Choose 'em: Expect Emmanuel Adebayor (12.85) to rediscover his scoring touch against Birmingham at a reduced price, and you will rarely find a better opportunity to back the dangerous Ricardo Fuller (6.14) than at home to Wolves. Dimitar Berbatov (11.16) remains very affordable and will be expected to make his mark against Blackburn.
Lose 'em: The Fantasist has been waiting for Darren Bent's (11.84) goals to finally dry up, but a knee injury could well bring his run to a shuddering halt regardless. Bobby ZamoraJo's (8.41) value is not good with Yakubu waiting in the wings and Louis Saha in fine form. (8.80) has had a surprisingly bright start to the season but don't expect that to continue against Liverpool, while
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